New concepts in chronic urticaria

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Chronic urticaria: new management options

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Histamine This is concentrated in granular depots within both mast cells and circulating basophils. The Type I mast cells found close to the arterioles and venules seem more important in this regard than the larger, regularly shaped, Type II cells scattered in the perivascular supporting tissues (Beaven, 1976a). Histamine release is accompanied by degranulation of the mast cells and basophils a...

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ژورنال

عنوان ژورنال: Current Opinion in Immunology

سال: 2008

ISSN: 0952-7915

DOI: 10.1016/j.coi.2008.09.005